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Biorefinery Research Group

Group leader: Csaba Fehér PhD

Webpage: https://biorefinery.bme.hu/en/ 

Address: H-1111, Budapest, Szent Gellért tér 4., CH. building 2nd Floor 264.

Short introduction:

The main research focus of the BioRefinery Research Group is the valorization of biomass and industrial by-products; the production of high value-added bioproducts, bio-based platform chemicals, and biofuels; as well as the development of biorefinery technologies. Our research activities include the physicochemical and enzymatic fractionation of biomass, the production and characterization of novel enzymes, the fermentation-based utilization of biomass fractions, the development of integrated biomass-based bioprocesses, and the modelling and techno-economic analysis of complete biorefinery technologies. Our group holds a leading position in Hungary in the field of lignocellulosic biomass utilization and biorefinery development.

Members: Csaba Fehér PhD, Kata Buda, Krisztina Gurzó

Main research topics:

  • Utilization of non-conventional yeasts in lignocellulose-based biorefinery processes
  • Process simulation and techno-economic analysis of biorefineries using AspenTech software
  • Development and optimization of novel fermentation processes to produce sugar alcohols and other bio-based platform molecules
  • Investigation and optimization of chemical and enzymatic fractionation of agro-industrial by-products
  • Application of lignocellulose and microbial biotechnology in emerging fields
  • Development of biotechnological solutions supporting the circular bioeconomy

Selected publications:

Ornella M Ontañon, Soma Bedő, Silvina Ghio, Mercedes M Garrido, Juliana Topalian, Dóra Jahola, Anikó Fehér, Maria Pia Valacco, Eleonora Campos, and Csaba Fehér. (2021) Optimization of xylanases production by two Cellulomonas strains and their use for biomass deconstruction Applied Microbiology and Biotechnology. 105(11): 4577–4588, https://doi.org/10.1007/s00253-021-11305-y (IF: 3.530)

Kristóf Hegedüs, Csaba Fehér, István Jalsovszky, Zoltán Kristóf, János Rohonczy, Elemér Vass, Attila Farkas, Tamás Csizmadia, Gernot Friedbacher and Peter Hantz. (2021) Facile isolation and analysis of sporopollenin exine from bee pollen. Scientific Reports, Nature Research, 11, 9952, https://doi.org/10.1038/s41598-021-87619-8 (IF: 3.998)

Juan Miguel Romero-García+, Csaba Fehér+, Cristóbal Cara, Encarnación Ruiz-Ramos, Eulogio Castro. (2022) Improved xylitol production from olive stones hydrolysates by biological detoxification. Journal of Cleaner Production 336, 130408 https://doi.org/10.1016/j.jclepro.2022.130408 (IF: 9.297)

Katarína Šuchová+, Csaba Fehér+, Jonas L. Ravn, Soma Bedő, Peter Biely, Cecilia Geijer. Cellulose- and xylan-degrading yeasts: Enzymes, applications and biotechnological potential. (2022) Biotechnology Advances s 59, 107981 https://doi.org/10.1016/j.biotechadv.2022.107981 (IF: 14.227)

Dorottya Vaskó; Júlia Domján; Bence Szűcs; László Bakk; Péter Hajdinák; György J. Marosi; Zsombor K. Nagy; Edit Hirsch; Csaba Fehér. (2023) Development and Comparison of Alternative Methods to Purify Adalimumab Directly from the Harvested Cell Culture Fluid. Food Technology and Biotechnology 61 (3) 339–349  https://doi.org/10.17113/ftb.61.03.23.8094 (IF 2.330)

 

Key partners:

Technical University of Denmark

Suranaree University of Technology

National Agricultural Technology Institute (Argentina)

University of Jaén

Chalmers University of Technology

University of Borås

Lund University

Aarhus University

IMDEA Materials Institute (Spain)

University of Antwerp

CIEMAT (Spain)